Dynamic Structure Factor of Membranes and Proteins: Past, Present and Future

by Prof. Rony Granek (Ben-Gurion University of the Negev)

Monday 18 Jan 2021, 14:30 → 15:30 Europe/Berlin

Zoom Webinar

In this talk I will discuss membrane and protein dynamics with respect to their detection by neutron spin echo (NSE).

Membranes: I will first review the so-called "Zilman-Granek theory" for membrane dynamic structure factor for the case of an embedding purely viscous solvent [1,2]. Next, I will discuss more recent generalizations and refinements: (i) A membrane surrounded by two semi-infinite continuous viscoelastic fluids [3]. (ii) A membrane surrounded by two semi-infinite structured viscoelastic fluids, such as semi-dilute polymer solutions [4]. (iii). Fluid-like, short-time, thickness fluctuations [5] that are based on the Brochard-Lennon "red blood cell" mode. Open questions and controversies will be discussed.

Proteins: A fractal-like approach to proteins, and the associated universal protein dynamics, will be presented [6-8]. I will further discuss the implications on the dynamic structure factor and NSE measurements on proteins in solution [9,10], with emphasis on the current limitations.

 

1. A. G. Zilman and R. Granek, Physical Review Letters, 77, 4788 (1996).
2. A. G. Zilman and R. Granek, Chemical Physics, 284, 195 (200.
3. R. Granek, Rony, Soft Matter, 7, 5281 (2011).
4. ‏R. Granek and H. Diamant, The European Physical Journal E, 41, 1 (2018).
5. R. Granek, The Journal of Physical Chemistry B, 123, 5665 (2019).
6. R. Granek and J. Klafter, Physical Review Letters 95, art. no. 098106 (2005).
7. R. Granek, Physical Review E 83, art. no. 020902(R), (2011).
8. S. Reuveni, R. Granek, and J. Klafter, PNAS 107, 13696 (2010).
9. S. Reuveni, J. Klafter, and R. Granek, Physical Review E 85, art. no. 011906 (2012).
10. S. Reuveni, J. Klafter, and R. Granek, Physical Review Letters 108, art. no. 068101 (2012).