Name: MLZ Conference: Neutrons for Health
Start: 2017-06-27T09:00:00+02:00
End: 2017-06-30T14:00:00+02:00
Location: No location set

MLZ Conference: Neutrons for Health

from Tuesday, June 27, 2017 (9:00 AM) to Friday, June 30, 2017 (2:00 PM)

Monday, June 26, 2017
Tuesday, June 27, 2017
9:00 AM Oral presentations I
9:00 AM - 12:00 PM
Contributions

9:00 AM Dynamics of concentrated protein solutions: from presbyopia to pharmaceutical formulations - Anna Stradner (Lund University, Division of Physical Chemistry)

9:30 AM A combined study based on simulations, analytical ultracentrifugation and SANS to elucidate the oligomers formed by Alzheimer’s Aβ peptide - Birgit Strodel (Forschungszentrum Jülich)

10:00 AM Hydrogen Bond Dynamics in Antipsychotics by Neutron Spectroscopy and Density Functional Theory - Jose Pereira (University Of Copenhagen)

10:50 AM The stratum corneum lipid composition and organization is key factor for the skin barrier: an integrated approach of lipid models and clinical studies - Joke Bouwstra (Division of Drug Delivery Technology, Leiden Academic Centre for Drug research, Leiden University)

11:20 AM Nanorheology: Using neutrons to discover the dynamics of biological membranes - Sebastian Jaksch (JCNS at MLZ)

11:40 AM Complex model membranes and neutron reflectivity: a mime for cell surface interactions - Valeria Rondelli (Università degli Studi di Milano)
12:00 PM Lunch
Lunch
12:00 PM - 1:00 PM
1:00 PM Oral presentations II
1:00 PM - 4:30 PM
Contributions

1:00 PM Solving biomedical puzzles using tiny” perdeuterated crystals for subatomic resolution X-Ray and neutron diffraction - Alberto Podjarny (IGBMC CNRS)

1:30 PM Neutrons to uncover the secrets of heme peroxidases - Peter Moody (University of Leicester)

2:00 PM Analysis of protein-ligand hydrogen bonding patterns in galectin-3 using neutron crystallography to guide drug design - Derek Logan (Lund University, Dept. of Biochemistry and Structural Biology)

2:50 PM Seeing H-atoms and protons: Enzyme mechanisms and drug design - Matthew Blakeley (Institut Laue-Langevin)

3:10 PM The structure of KRas at the lipid membrane - Frank Heinrich (Carnegie Mellon University)

3:30 PM How PEGylation of protein may change its structure and biological functionality - Karol Ciepluch (Forschungszentrum Jülich)

3:50 PM Small Angle Neutron Scattering Instrument KWS1 for Protein Structure Determination - Henrich Frielinghaus (JCNS at MLZ)

4:10 PM Drug development using information from Neutron protein crystallography - Tobias Schrader (JCNS at MLZ)
4:30 PM Poster session A
4:30 PM - 6:30 PM
Contributions

4:30 PM Drug-Polymer and Lipid Bio-Nanoparticles for Chemo-Therapy and Cancer Prevention - Paricahrt Thummarati

4:35 PM Magnetic Drug Targeting (MDT)-assisted neutron capture therapy - Harald Unterweger (Section of Experimental Oncology and Nanomedicine (SEON), Universitätsklinikum Erlangen)

4:40 PM Dynamics in Denatured Proteins Investigated with Neutron Spin-Echo Spectroscopy NSE - Felix Ameseder (Forschungszentrum Jülich)

4:45 PM Hydration-dependent dynamics of human telomeric oligonucleotides investigated by inelastic neutron scattering - Marialucia Longo (JCNS at MLZ)

4:50 PM Investigation of self-assembling biopolymers of hGBP1 in the native farnesylated state - Charlotte Lorenz (Forschungszentrum Jülich)

4:55 PM MIMAC-‐FastN : a directional fast neutron spectrometer - Nadine Sauzet (LPSC)

5:00 PM Effect of membrane active drugs on the structure of lipid bilayers - Manuchar Gvaramia (JCNS at MLZ)

5:05 PM mRNA Nanoparticles for parenteral Therapy - Thomas Nawroth (Gutenberg-University, Pharmaceutical Technology, Staudingerweg 5)

5:10 PM The Neutron Spin Echo Spectrometer @ SNS (NSE-SNS) - Laura Roxana Stingaciu (FZJ-JCNS1@FRMII)

5:15 PM Studying Biological Systems over a Wide Length Scale from Angstrom to Micrometer Sizes at the SANS Diffractometer KWS-2 - Andreas Stadler (FZ Jülich)

5:20 PM The cold chopper spectrometer TOFTOF and its application to Biology - Wiebke Lohstroh

5:25 PM Pilot studies on NCT feasibility to treat neurotoxic protein aggregates - Nicoletta Protti (National Institute of Nuclear Physics INFN, Pavia Unit)

5:30 PM Exploring dynamic processes in biological systems with SPHERES - Laura Roxana Stingaciu (JCNS at MLZ)
7:00 PM Dinner
Dinner
7:00 PM - 9:00 PM
Wednesday, June 28, 2017
9:00 AM Oral presentations III
9:00 AM - 12:00 PM
Contributions

9:00 AM Neutrons against Cancer - Wolfgang Sauerwein (University Duisburg-Essen, University Hospital Essen,)

9:30 AM Development of Intensity Modulated Fast Neutron Therapy at the University of Washington - Robert Emery (University of Washington)

10:00 AM Characterisation of the secondary fast and ultrafast neutrons emitted in Particle Therapy with the MONDO experiment - Michela Marafini (Centro Fermi, Museo Storico della Fisica e Centro Studi e RIcerche E.Fermi / INFN Sezione Roma)

10:50 AM Neutron Irradiation Therapy – the clinicians view - Andrea Posch (Univ. Klinik für Radioonkologie-Strahlentherapie Innsbruck)

11:20 AM Fast neutron medical treatment – a status report - Franz-Michael Wagner (MLZ, TUM)
12:00 PM Lunch
Lunch
12:00 PM - 1:00 PM
1:00 PM Oral presentations IV
1:00 PM - 3:00 PM
Contributions

1:00 PM A passive mechanism of antibiotic resistance - the Impermeable Bacterial Outer Membrane - Jeremy Lakey (Newcastle University)

1:30 PM Neutron Reflectometry yields distance-dependent structures of interacting membranes displaying synthetic polymers and wild-type bacterial lipopolysaccharides - Ignacio Rodriguez-Loureiro (Max Planck Institute of Colloids and Interfaces)

1:50 PM Structure and Fluctuations of Lipid Nonlamellar Phases Deposited at the Solid–Liquid Interface - Olaf Soltwedel (MLZ, TUM)
3:00 PM Conference trip

3:00 PM - 7:00 PM

7:00 PM Conference dinner

7:00 PM - 10:00 PM
Thursday, June 29, 2017
9:00 AM Oral presentations V
9:00 AM - 12:00 PM
Contributions

9:00 AM A brief history of the evolution of carrier-free Lutetium-177 into a globally established isotope platform for a new class of targeted cancer therapeutics - Oliver Buck (ITM Isotopen Technologien München AG)

9:30 AM Production of Mo-99/Tc-99m at FRM II - Status of the Project - Heiko Gerstenberg (FRM II, TUM)

9:50 AM Neutron activation of QuiremSpheres® in FRM II - Johannes Nijsen (Quirem Medical)

10:40 AM Nanotechnology-based Drug Delivery in Oncology - Targeted Chemotherapy and Examples for specific Radioenhancement - Rainer Tietze (Universitätsklinikum Erlangen)

11:10 AM Target Nanoparticles for Cancer Therapy with Neutrons and Photons - Thomas Nawroth (Gutenberg-University, Pharmaceutical Technology)

11:30 AM Neutron radiobiology experiments at ILL for improving Boron Neutron Capture Therapy - Ignacio Porras (Universidad de Granada)
12:00 PM Lunch
Lunch
12:00 PM - 1:00 PM
1:00 PM Oral presentations VI
1:00 PM - 5:40 PM
Contributions

1:00 PM Neutron Scattering and Drug Discovery - Jeremy Smith (University of Tennessee/Oak Ridge National Laboratory)

1:30 PM SANS studies of health-related micelles and “hybrid” vesicles made of copolymers, polypeptides and phospholipids - Oliver Sandre

2:00 PM Combining Neutrons and Molecular Simulations for Membrane Biophysics - Alexandros Koutsioumpas (JCNS at MLZ)

2:20 PM Complementary small-angle neutron and X-ray scattering studies of Mitoxantrone loaded iron oxide nanoparticle complex for magnetic drug targeting - Artem Feoktystov (JCNS at MLZ)

3:10 PM Multimodal Iron-Oxide Nanoparticles: from Design to in vivo Applications - Luigi Paduano (Department of Chemical Sciences, University of Naples "Federico II")

3:30 PM Advanced Characterization of invasive medical devices using neutron techniques - Massimo Rogante (Rogante Engineering Office)

3:50 PM Protein-solvent dynamical coupling in native proteins amyloid fibers and nano-engineered protein-polymer hybrids - Giorgio Schiro (CNRS - Institut de Biologie Structurale)

4:20 PM High hydrostatic pressure specifically affects molecular dynamics and shape of low-density lipoprotein particles - Judith Peters (Université Grenoble Alpes)

4:40 PM Photoactivation Reduces Side-Chain Dynamics of a LOV Photoreceptor - Andreas Stadler (Forschungszentrum Jülich)

5:00 PM The neutron spin echo spectrometer J-NSE: switching on the slow motion - Olaf Holderer (JCNS at MLZ)
5:20 PM Poster Session B

5:20 PM - 7:00 PM

7:00 PM Dinner
Dinner
7:00 PM - 9:00 PM
Friday, June 30, 2017
9:00 AM Oral presentations VII
9:00 AM - 11:00 AM
Contributions

9:00 AM Filling in the gaps: improving our quality of life by understanding hydrogen bonds - Heloisa Bordallo (University of Copenhagen - Niels Bohr Institute & ESS ERIC)

9:30 AM Towards the structure of native bacterial cellulose: Is Brown's model accurate? - Ruslan Smyslov (Institute of Macromolecular Compounds of Russian Academy of Sciences; PNPI NRC KI)

9:50 AM Neutrons and Health: The First Ten Years of Food Science @ ANSTO - Elliot Gilbert (ANSTO)
11:30 AM Valedictory lunch
Valedictory lunch
11:30 AM - 12:30 PM

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