Speaker
Dr
Holger von Moeller
(MOLOX GmbH)
Description
An efficient fragment screening pipeline was set up for a global player from pharmaceutical industry. 1000 crystals were prepared at NUVISAN ICB's high-throughput crystallography platform. Beamline P14 at EMBL Hamburg was chosen for data collection and MOLOX performed this service here. Data processing and structure determination was done by the client. More than 87% of the crystals yielded a dataset of sufficient quality for downstream analyses. Median resolution over all datasets was 1.84 Å.
Primary authors
Christian Becke
(MOLOX GmbH)
Dr
Holger von Moeller
(MOLOX GmbH)
Dr
Gleb Bourenkov
(EMBL Hamburg)
Dr
Marina Nikolova
(EMBL Hamburg)
Dr
Martina Schaefer
(Nuvisan ICB)
Moises Bueno
(EMBL Hamburg)
Dr
Saravanan Panneerselvam
(EMBL Hamburg)
Dr
Sophie Zimmermann
(MOLOX GmbH)
Dr
Stefan Fiedler
(EMBL Hamburg)
Tammo Stevens
(Nuvisan ICB)
Dr
Thomas R. Schneider
(EMBL Hamburg)
Vamsee Krishna Palnati
(EMBL Hamburg)
