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14–17 Mar 2022
Europe/Berlin timezone

Structural characterization of reaction intermediates of the copper-dependent formylglycine-generating enzyme

14 Mar 2022, 15:50
20m

Speaker

Florian Seebeck

Description

O2 activation is central elementary step in many biological reactions. The formylglycine generating enzyme (FGE) is a mononuclear copper enzyme that appears to follow an unusual strategy for O2 activation. In this presentation I will summarize our past and present efforts to visualize individual states of the enzyme on its path from the resting state to the reactive Michaelis Menten complex and beyond.

Primary author

Florian Seebeck

Presentation materials