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14–17 Mar 2022
Europe/Berlin timezone

Using AlphaFold to understand multi-domain proteins from SARS-CoV-2

17 Mar 2022, 09:00
20m
Talk Covid-19 COVID-19 Research

Speaker

Mr Maximilian Edich (Institut für Nanostruktur und Festkörperphysik)

Description

Here, we demonstrate the use of AlphaFold on proteins from SARS-CoV-2. While the solved structures only cover a part of the viral genome we have plenty of annotated protein-coding genes, which structures can now be predicted computationally. We discuss both the benefits as well as the potential shortcomings of these predictions and show how they can be combined with information from other tools and experimentally determined structures to get new insights into the structural biology of the virus.

Primary author

Mr Maximilian Edich (Institut für Nanostruktur und Festkörperphysik)

Presentation materials