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14–17 Mar 2022
Europe/Berlin timezone

Assigning the absolute configuration of liquid chiral molecules by capillary crystallization

17 Mar 2022, 10:00
20m
Talk Structural Chemistry & New crystal structures Structural Chemistry II

Speaker

Nils Nöthling

Description

If the compound of interested is liquid under ambient conditions, conventional crystallization methods are not able to deliver suitable crystals for X-ray diffraction. In situ capillary crystallization is used for the crystallization of enantiopure liquids to determine the absolute configuration. The main advantages of the method are that only a small sample amount (~5 mg) is required and that there is no need to rely on reference substances to determine the absolute configuration.

Primary author

Nils Nöthling

Co-authors

Dr Richard Goddard Mr Michael Patzer Christian W. Lehmann

Presentation materials