Speaker
Julia L. Kowal
Description
The formylglycine-generating enzyme (FGE) plays a key role in the posttranslational modification of the active site of all known human sulfatases. Previously crystallized structures of FGE are missing a surface loop that had to be cleaved off prior to crystallization. Here, we report the first crystallization of human FGE including this loop.
Primary author
Julia L. Kowal
Co-authors
Dr
Sarfaraz Alam
Dr
Karthikeyan Radhakrishnan
Prof.
Hartmut H. Niemann
