Speaker
Sophie Combet
(LLB)
Description
SAXS and SANS combined with modeling have proved to be essential techniques in structural biology when the classical high-resolution methods are not appropriate. The “contrast matching” method in SANS is particularly suitable to specifically probe membrane proteins by contrast-matching their amphiphilic environment. I will illustrate this feature with TSPO translocator protein, a ubiquitous and functionally important membrane protein used as a pharmacological marker in neuroimaging.
Primary author
Sophie Combet
(LLB)