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27–30 Jun 2017
Europe/Berlin timezone

Exploring dynamic processes in biological systems with SPHERES

27 Jun 2017, 17:30
5m
Poster Main conference Poster session A

Speaker

Dr Laura Roxana Stingaciu (JCNS at MLZ)

Description

The neutron backscattering spectrometer SPHERES (SPectrometer for High Energy RESolution) at MLZ is a third generation backscattering spectrometer with focusing optics and phase-space transform (PST) chopper. It covers a dynamic range of ± 31μeV with a high resolution of about 0.66μeV and a good signal-to-noise ratio. The intensity has been recently doubled by the upgrade of the PST chopper. Further improvement of the instrument performance is expected from the planned upgrade of the focusing guide and the introduction of a background chopper. SPHERES enables investigations on a broad range of scientific topics. It is in particular sensitive to the incoherent scattering from hydrogen and allows to access dynamic processes up to a timescale of a few ns. Therefore it is well suited to study dynamic processes in various biological systems. Selective deuteration allows for example to follow the mobility of water on the surface of proteins (e.g. Y. Fichou et al., PNAS 112, 6365 (2015)) or measure internal protein motions (e.g. A. Stadler et al., Biophysical Journal 110, 1064 (2016)).

Primary author

Michaela Zamponi (JCNS at MLZ, Forschungszentrum Juelich GmbH)

Co-authors

Dr Laura Roxana Stingaciu (JCNS at MLZ) Dr Marina Khaneft (JCNS at MLZ)

Presentation materials

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