Conveners
Bio-inspired Soft Matter Systems
- Valeria Rondelli (Università degli Studi di Milano)
- Tobias Schrader
Many pharmaceuticals products are stored as frozen solutions or in amorphous solid (lyophilized) phases to minimize chemical and physical degradation during their shelf life.
However, freezing and drying per se could also destabilize proteins. There are multiple protein degradation pathways, including, e.g., oxidation, deamidation, and aggregation. Protein aggregation, in particular, can...
Terahertz time domain spectroscopy (THz-TDS) revealed that fast (rotational) water dynamics depend on phospholipid headgroup structure by comparing PC and PE [1], but the comparison between them for the loosely and tightly bound (translational) hydration water (HW) observed for DMPC by quasi-elastic neutron scattering (QENS) [2], is still not revealed. We have done QENS experiments on the...
Heat transport properties in solid materials are driven by the accumulative contributions of phonons spanning a wide range of mean free paths. Porous, hygroscopic, nanocellulose foams exhibit super-insulating properties, highly dependent on their moisture content, and through theoretical estimations and simulations, it has been shown that the heat transfer in such materials is dominated by...
In recent years many studies into green solvents have been undertaken and deep eutectic solvents (DES) have emerged as environmentally friendly alternatives in many fields, such as separation processes, metal processing, biocatalysis and electrochemistry.[1] DES are solvents obtained through the complexation of organic compounds, where the interaction between the precursors promotes a...
The removal of water from biological tissue by desiccation or freezing is associated with dramatic changes to membrane structure, often leading to cellular (and organismal) death. We now understand that much of the damage to under these conditions is physical, rather than biochemical. The maintenance of membrane structure is vital for cellular function, but these structures can be affected by...
